Target Health Blog

March

Note from client: WOOHOO! Last patient visit (LPV) occurred today!!!

March 27, 2017

,News

We are always delighted to receive feedback directly from our clients. This recent email made our entire week!

Kfar Shaul Mental Health Center in Jerusalem

March 20, 2017

,History of Medicine

Kfar Shaul Mental Health Center, established in 1951, is an Israeli public psychiatric hospital located between Givat Shaul and Har Nof, Jerusalem. It is affiliated with the Hadassah Medical Center and the Hebrew University of Jerusalem. The hospital is Jerusalem's designated psychiatric hospital for tourists who display mental health disturbances, and is widely known for its research on Jerusalem Syndrome.

Jerusalem Syndrome

March 20, 2017

,Quiz

A bizarre mental illness that affects people visiting Israel is called Jerusalem Syndrome.

Conference: eSource Data in Clinical Investigations - May 2-3, 2017 - Doubletree Center City, Philadelphia, Pa

March 20, 2017

,What's New

Target Health Inc. is pleased to announce that Dr. Jules Mitchel will be presenting at CBI's 4th Annual Bootcamp on eSource Data in Clinical Investigations. The conference aims to initiate meaningful dialogues, through collaborative sessions and investigative case studies, around early successes, challenges and failures, so that one can build an eSource adoption business case for senior leadership addressing balance of risk and cost.

Curry Eggplant Pancake with Wide Variety of Toppings

Medium rare lamb pieces, cooked in oil and garlic with a fig reduction, is the topping on the eggplant pancake that you see above. It's garnished with chopped scallion and served with fresh mango and mango chutney.

Helping to Speed Cures and Treatments to Patients

March 20, 2017

,Regulatory

The FDA is committed to helping deliver innovative, safe, and effective treatments and cures to the patients who need them as quickly as possible. To achieve this goal, FDA has implemented a variety of expedited review programs and are working to help shorten the development time before a product is even submitted for FDA review.

Impaired Glucose Homeostasis in First-Episode Schizophrenia

March 20, 2017

,Psychiatry

Schizophrenia is associated with an increased risk of type 2 diabetes. However, it is not clear whether schizophrenia confers an inherent risk for glucose dysregulation in the absence of the effects of chronic illness and long-term treatment. As a result, a study published in JAMA Psychiatry (2017;74:261-269) conducted a meta-analysis examining whether individuals with first-episode schizophrenia already exhibit alterations in glucose homeostasis compared with controls.

African-Specific Genomic Variant Associated With Obesity

March 20, 2017

,

Obesity is a global health problem, contributing to premature death and morbidity by increasing a person's risk of developing diabetes, hypertension, heart disease and some cancers. While obesity mostly results from lifestyle and cultural factors, including excess calorie intake and inadequate levels of physical activity, it has a strong genomic component. The burden of obesity is, however, not the same across U.S. ethnic groups, with African-Americans having the highest age-adjusted rates of obesity. Interestingly, most of the genomic studies conducted on obesity to date have been in people of European ancestry, despite an increased risk of obesity in people of African ancestry.

Mutual Recognition Promises New Framework for Pharmaceutical Inspections for United States and European Union

March 13, 2017

,Regulatory

The United States and the European Union (EU) completed an exchange of letters to amend the Pharmaceutical Annex to the 1998 U.S.-EU Mutual Recognition Agreement. Under this agreement, U.S. and EU regulators will be able to utilize each other's good manufacturing practice inspections of pharmaceutical manufacturing facilities. The amended agreement ?represents the culmination of nearly three years of U.S. FDA and EU cooperation as part of the Mutual Reliance Initiative and will allow the FDA and EU drug inspectors to rely upon information from drug inspections conducted within each other's borders. Ultimately, this will enable the FDA and EU to avoid the duplication of drug inspections, lower inspection costs and enable regulators to devote more resources to other parts of the world where there may be greater risk.

Blood-based NfL: A Biomarker for Differential Diagnosis of Parkinsonian Disorder

March 13, 2017

,Neurology

In order t0 improve the diagnostic workup of parkinsonian disorders, a study published online in Neurology (2017; 88:930-937), was performed to determine if blood neurofilament light chain (NfL) protein can discriminate between Parkinson disease (PD) and atypical parkinsonian disorders (APD) with equally high diagnostic accuracy as CSF NfL.

Chimpanzee Adenovirus Vector Ebola Vaccine

March 13, 2017

,Tropical Medicine

The unprecedented 2014 epidemic of Ebola virus disease (EVD) prompted an international response to accelerate the availability of a preventive vaccine. A replication-defective recombinant chimpanzee adenovirus type 3-vectored ebolavirus vaccine (cAd3-EBO), encoding the glycoprotein from Zaire and Sudan species, that offers protection in the nonhuman primate model, was rapidly advanced into phase 1 clinical evaluation.

Stephan Wolfram (1959 to Present)

March 13, 2017

,History of Medicine

Target Health Inc. is an eCRO, that creates software for clinical trials and is interested in how Big Data is sorted through, especially for application to medical research, and clinical trials.

Sharing Patient Records Is Still a Digital Dilemma

March 13, 2017

,Quiz

Privacy and Security, are still important issues connected with Electronic Health Records (EHR). EHRs allow providers to use information more effectively to improve the quality and efficiency of your care, but EHRs do not change the privacy protections or security safeguards that apply to health information. EHRs Personal Health Records (PHR) are electronic versions of the 1) ___ charts in doctor's or other health care provider's offices. An EHR may include one's medical history, notes, and other information about one's health including symptoms, diagnoses, medications, lab results, vital signs, immunizations, and reports from diagnostic tests such as x-rays. The information in EHRs can be shared with other organizations if the computer systems are set up to talk to each other. Information in these records should only be shared for purposes authorized by law or by individuals. There are privacy rights whether information is stored as a paper record or stored in an electronic form. The same federal laws that already protect health information also apply to information in EHRs.

Climate Change: Springtime in NYC: First a Snow Storm, then Sun and Flowers

March 13, 2017

,What's New

The photo below was taken in the front gardens of our building in NYC showing the crocuses pushing through.

Extreme Temperatures May Increase Risk For Low Birth Weight

March 6, 2017

,Neonatology

Low birth weight refers to infants weighing less than 5.5 lbs. at birth. Infants may be of low birth weight because they are born prematurely, while others may be of low birth weight even though they have completed the 37-40 weeks that is considered to be a term pregnancy. Some are otherwise healthy, but are genetically predisposed to small size. Others are of low birth weight because of an underlying health problem — illness, infection or a failure to grow in the womb. Compared to infants of normal weight, low birth weight infants may be at higher risk for infection and developmental delays.

Mixed Results of Trials of Testosterone Therapy in Older Men

March 6, 2017

,Men's Health

Recent studies have yielded conflicting results as to whether testosterone treatment increases cardiovascular risk and/or slows down the rate of cognitive function decline with age. As a result, two studies (Testosterone Treatment and Cognitive Function in Older Men With Low Testosterone and Age-Associated Memory Impairment; Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone); were reported on 21 February 2017 in JAMA, which tested the hypotheses as to whether testosterone treatment of older men with low testosterone 1) slows progression of noncalcified coronary artery plaque volume and 2) is associated with improved verbal memory and other cognitive functions and age-associated memory impairment (AAMI).

New Website Launched

March 6, 2017

,What's New

Target Health Website has a new look, although the banner designed by CEO Joyce Hays, remains as well as the famous Leaping Dog, a feature of our website from inception. We are also very proud of our publications, many of which are prescient and trailblazing.

Approval of First Treatment for Nocturnal Frequent Urination to Overproduction of Urine

March 6, 2017

,Regulatory

Nocturia (wakening at night to urinate) is a symptom that can be caused by a wide variety of conditions, such as congestive heart failure, poorly controlled diabetes mellitus, medications, or diseases of the bladder or prostate.

History of Cupping as a Medical Device

According to traditional Chinese medicine (TCM), cupping is a method of creating a vacuum on the patient’s skin to dispel stagnation (stagnant blood and lymph), thereby improving qi flow, in order to treat respiratory diseases such as the common cold, pneumonia and bronchitis. Cupping also is used on back, neck, shoulder and other musculoskeletal conditions.